DMT-dG(Ib) Phosphoramidite CAS 93183-15-4 Purity ≥99.0% (HPLC) DNA Phosphoramidites

Short Description:

Chemical Name: DMT-dG(Ib) Phosphoramidite

CAS: 93183-15-4

Purity: ≥99.0% (Reversed Phase HPLC)

Purity: ≥98.0% (31P-NMR)

Appearance: White to Off-White Powder

DNA Phosphoramidites for Oligonucleotide Synthesis

Contact: Dr. Alvin Huang

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Product Detail

Product Tags

DNA Phosphoramidites:

DMT-dC(bz) Phosphoramidite	CAS 102212-98-6
DMT-dT Phosphoramidite	CAS 98796-51-1
DMT-dA(Bz) Phosphoramidite	CAS 98796-53-3
DMT-dG(Ib) Phosphoramidite	CAS 93183-15-4
DMT-dC(ac) Phosphoramidite	CAS 154110-40-4
DMT-dG(dmf) Phosphoramidite	CAS 330628-04-1

93183-15-4 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of DMT-dG(Ib) Phosphoramidite (CAS: 93183-15-4) with high purity and low impurities. DNA phosphoramidites for oligonucleotide synthesis. Used in the synthesis of DNA and RNA molecules. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase DMT-dG(Ib) Phosphoramidite or other products, please contact us by e-mail: alvin@ruifuchem.com

93183-15-4 - Chemical Properties:

Chemical Name	DMT-dG(Ib) Phosphoramidite
Synonyms	DMT-dG(ib) Pharmadite; dG(N-ibu) Phosphoramidite; Guanosine-BCE-Phosphoramidite; N2-Isobutyryl-5'-O-(4,4'-Dimethoxytrityl)-2'-Deoxyguanosine-3'-(2-Cyanoethyl-N,N-Diisopropyl)phosphoramidite; 5'-O-[Bis(4-Methoxyphenyl)(phenyl)methyl]-3'-O-[(2-Cyanoethoxy)(diisopropylamino)phosphino]-2'-Deoxy-N-Isobutyrylguanosine; N-(2-Methyl-1-Oxopropyl)-5′-O-[bis(4-Methoxyphenyl)phenylmethyl]-2′-Deoxyguanosine; 3′-[2-Cyanoethyl N,N-bis(1-Methylethyl)phosphoramidite]
Stock Status	In Stock, Commercial Production
CAS Number	93183-15-4
Molecular Formula	C44H54N7O8P
Molecular Weight	839.93 g/mol
Density	1.22 at 20℃
Store Under Inert Gas	Store Under Inert Gas
Sensitive	Moisture Sensitive, Heat Sensitive
Solubility	Soluble, Clear
Storage Temperature	Sealed in Dry, Store at -20℃, Protect From Light, Stored Under Nitrogen
Shipping Conditions	Shipped Under Ambient Temperature For Short Term
Expiration Date	12 Months From Date of Receipt
COA & MSDS	Available
Origin of Product	Shanghai, China
Product Categories	DNA Phosphoramidites
Caution	Not For Human or Veterinary Use. For Research Use Only.
Brand	Ruifu Chemical

93183-15-4 - Specifications:

Items	Specifications	Results
Appearance	White to Off-White Powder	White Powder
Clarity After Dissolution (Visual)	The Solution is Clear with No Insolubles	Clear
Water Content	≤0.30% (Karl Fischer)	Conforms
Purity / Analysis Method	≥99.0% (Reversed Phase HPLC)	99.61%
Purity / Analysis Method	≥99.0% (31P-NMR)	Conforms
Residual Solvent Content	≤3.00% (GC)	Conforms
DMT-dG(ib) Cyanoethyl-H-Posphonate	≤0.30% (Reversed Phase HPLC)	Conforms
DMT-dG(ib) Phosphoramidate	≤0.30% (Reversed Phase HPLC)	Conforms
DMT-dG(ib)-Diisopropylamino-H-Phosphonate	≤0.30% (Reversed Phase HPLC)	Conforms
Single Unspecified Impurity	≤0.10% (Reversed Phase HPLC)	Conforms
1H NMR Spectrum	Conforms to Structure	Conforms
Conclusion	Has been tested & complies with the given specifications

93183-15-4 - Package/Storage/Shipping:

Package: 1g/10g/50g/100g/1kg/10kg/bulk. Amber glass screw cap vial or white plastic bottle.
Storage Condition: Keep the container tightly closed. Sealed in dry, store in freezer, store at -20℃, protect from light, stored under nitrogen. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.

93183-15-4 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

93183-15-4 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

93183-15-4 - Risk and Safety:

Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	2934.99.9001

93183-15-4 - Application:

DMT-dG(Ib) Phosphoramidite (CAS: 93183-15-4) is a type of nucleoside analog used in the synthesis of DNA and RNA molecules. It is a modified nucleoside that consists of a deoxyribose sugar, a nitrogenous base (guanine) and a phosphoramidite linker group. The phosphoramidite linker group gives DMT-dG(ib) Phosphoramidite its unique properties, allowing it to be used in a variety of applications.
DMT-dG(Ib) Phosphoramidite is a chemical compound used in scientific experiments, particularly in DNA sequencing. This compound is a key component used in the synthesis of modified oligonucleotides, which have various applications in biotechnology.

93183-15-4 - Scientific Research Applications:

DMT-dG(Ib) Phosphoramidite (CAS: 93183-15-4) has a variety of applications in scientific research. It can be used to create DNA and RNA molecules for a variety of purposes, such as gene cloning and gene expression studies. It can also be used to create modified nucleotides for use in antisense oligonucleotides and other therapeutic applications. Additionally, it can be used to create nucleotides with modified bases, such as 2’-deoxyinosine, which can be used to study the structure and function of DNA and RNA.

93183-15-4 - Mechanism of Action:

DMT-dG(Ib) Phosphoramidite (CAS: 93183-15-4) works by forming a covalent bond between the 5’-hydroxyl group of the DMT-dG(ib) Phosphoramidite base and the 5’-dimethoxytrityl (DMT) group. This bond is then further stabilized by the addition of a phosphoramidite linker group. This bond is strong and stable, allowing the nucleotide to remain intact throughout the synthesis process.

93183-15-4 - Biochemical and Physiological Effects:

DMT-dG(Ib) Phosphoramidite (CAS: 93183-15-4) does not have any direct biochemical or physiological effects. It is not a drug and does not interact with any biological targets. However, it can be used to create modified nucleotides that do have biochemical and physiological effects. For example, antisense oligonucleotides created with DMT-dG(ib) Phosphoramidite can bind to mRNA and inhibit its translation into proteins, thus having a direct effect on gene expression.

93183-15-4 - Advantages and Limitations for Lab Experiments:

The main advantage of DMT-dG(Ib) Phosphoramidite (CAS: 93183-15-4) is that it is a cost-effective and efficient method for synthesizing DNA and RNA molecules. It is also relatively easy to use and can be used to create large amounts of nucleotides in a short amount of time. However, it does have some limitations. For example, it cannot be used to create modified nucleotides with modified bases, such as 2’-deoxyinosine, which are necessary for some applications. Additionally, it is not suitable for creating very large DNA or RNA molecules.

93183-15-4 - Current State of Research:

Research on DMT-dG(Ib) Phosphoramidite is ongoing, with researchers exploring new applications for the compound in the field of biotechnology. In recent years, there has been an increasing interest in the development of modified oligonucleotides containing DMT-dG(Ib) Phosphoramidite for gene therapy applications.

93183-15-4 - Future Directions:

There are a variety of potential future directions for DMT-dG(Ib) Phosphoramidite (CAS: 93183-15-4). One potential direction is to develop new methods for synthesizing modified nucleotides with modified bases, such as 2’-deoxyinosine. Additionally, methods could be developed to create larger DNA and RNA molecules using DMT-dG(ib) Phosphoramidite. Finally, new applications for DMT-dG(Ib) Phosphoramidite, such as therapeutic applications, could be explored. As well as the exploration of its potential applications in gene therapy and diagnostics.