(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS 85977-52-2 Purity ≥99.0% e.e.≥99.0% Palonosetron Hydrochloride Intermediate Factory
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of (S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid (CAS: 85977-52-2) with high quality, intermediate of Palonosetron Hydrochloride (CAS: 135729-62-3). Ruifu Chemical has been supplying pharmaceutical intermediates and APIs, fine chemicals more than 15 years. Ruifu Chemical can provide competitive price, excellent service. Purchase please contact us by e-mail: alvin@ruifuchem.com
Commercial Supply Palonosetron Hydrochloride and Related Intermediates:
(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R)-1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API
Chemical Name | (S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid |
Synonyms | (1S)-1,2,3,4-Tetrahydronaphthalene-1-Carboxylic acid |
CAS Number | 85977-52-2 |
Stock Status | In Stock, Commercial Production |
Molecular Formula | C11H12O2 |
Molecular Weight | 176.21 |
Density | 1.186±0.06 g/cm3 |
Melting Point | 54.0~56.0℃ |
Boiling Point | 342.7°C at 760 mmHg |
Refractive Index | 1.576 |
COA & MSDS | Available |
Origin of Product | Shanghai, China |
Product Categories | Pharmaceutical Intermediates |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White or Almost White Crystalline Powder |
Chemical Purity | ≥99.0% |
Enantimoer Excess | e.e. ≥99.0% |
Isomer Impurity | ≤1.0% |
Loss on Drying | ≤0.50% |
Relate Substance | ≤1.0% |
Moisture (K.F) | ≤1.0% |
Specific Rotation [α]D20 | -59.0°~ -63.0°(C=0.3 in Benzence) |
Heavy Metals | ≤20ppm |
Storage | 5-8℃ Airtightness |
Test Standard | Enterprise Standard |
Usage | Palonosetron Hydrochloride (CAS: 135729-62-3) Intermediates |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry, well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
Risk Codes R22 - Harmful if swallowed
R36 - Irritating to the eyes
R51 - Toxic to aquatic organisms
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S24/25 - Avoid contact with skin and eyes.
HS Code 2916399090
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid (CAS: 85977-52-2) with high quality. It is an intermediate typically in the synthesis of Palonosetron Hydrochloride (CAS: 135729-62-3).
Palonosetron Hydrochloride (CAS: 135729-62-3) is a novel 5-HT3 receptor antagonist launched as an injectable agent for the prevention of acute and delayed nausea and vomiting associated with cancer chemotherapy. It has a much longer half-life (~40 h) than the other currently available 5-HT3 antagonists, which provides efficacy advantages in the prevention of delayed nausea and vomiting that typically occurs after 24 h and up to six days post chemotherapy administration. With 1,2,3,4-tetrahydro-1-Naphthoic Acid as the starting material, the split, amination, reduction, cyclization, salt of palonosetron hydrochloride granisetron.